The San Francisco 49ers are set to host the Detroit Lions at Levi's Stadium in Santa Clara, California, on Monday, December ...

Head coach Kyle Shanahan offered an update on Saturday regarding the recovery of San Francisco 49ers wide receiver Brandon ...

San Francisco 49ers RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters on Saturday following the team's final practice before their ...

The San Francisco 49ers entered Sunday's matchup against the Miami Dolphins without two key offensive contributors: running ...

The San Francisco 49ers face slim odds of landing a top-nine pick in the 2025 NFL Draft. The Carolina Panthers and New York ...

The NFL's much-discussed new rule against hip-drop tackles has only produced one penalty flag this season, against Carolina's ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Saturday's practice as the team prepares for its Week ...

The 49ers are set to head into their "Monday Night Football" contest with the Detroit Lions a little worse for the wear, ...

Tight end George Kittle is known for being one of the most upbeat and positive personalities in the San Francisco 49ers ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week's game with a ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...