Although the basic pathology of MS was already recognized in the 18th century, its causes and pathogenesis remain elusive. The most widely accepted theory is that MS develops in genetically ...

When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered ...

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the CNS. 1 In early disease, active bouts of demyelination are followed by periods of remission, and relapses are ...

Mechanisms of Multiple Sclerosis. The pathogenesis of MS involves the initiation and perpetuation of inflammatory mediators, which leads to apoptosis of oligodendrocytes and damage to the myelin ...

Epstein-Barr Virus. Epstein-Barr virus (EBV) has long been postulated to play a role in the pathogenesis of MS, but that connection received a solid boost in 2022, when Alberto Ascherio, MD, DrPH ...

ST. LOUIS -- African Americans with multiple sclerosis have a more robust immunologic response than whites, which may explain the greater severity of symptoms among blacks, investigators here found.

“Multiple sclerosis (MS) ... “While progress has been made in defining the immune system’s role in MS pathophysiology, the contribution of intrinsic CNS cell dysfunction remains unclear. ...

In fact, a study of 801 MS cases from more than 10 million active-duty military personnel over 20 years found that EBV ...

Following a competitive selection process, Ashlyn Anderson was chosen as the recipient of the inaugural Tanner MS Scholar Award. Ashlyn is a 4 th year PhD student at the University of Alabama at ...

The hypothetical etiological mechanisms of VZV infection in MS pathogenesis could be the sudden activation of latent VZV in the neural ganglia, which would spread to the CNS, ...