When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered ...

Epstein-Barr virus (EBV) has long been postulated to play a role in the pathogenesis of MS, but that connection received a solid boost in 2022, when Alberto Ascherio, MD, DrPH, of Harvard T. H ...

The pathogenesis of MS consists of two arms: an inflammatory arm, which is associated with a potent cellular and humoral immune response against potential CNS antigen (s), and a neurodegenerative ...

Cognitive impairment is a recognized sequela of the demyelinating disorder multiple sclerosis (MS). Various studies have attempted to quantify the percentage of patients with cognitive impairment in ...

Glia-enriched cultures from a primary progressive multiple sclerosis iPSC line showing astrocytes (yellow), oligodendrocytes (cyan), and neurons (magenta). [New York Stem Cell Foundation] ...

Credit: Getty Images Some viral infections have been implicating in either driving the pathophysiology of multiple sclerosis or making it worse. Many social scientists have termed the age we live ...

The researchers used data from a genome-wide association study (GWAS) — including 14,802 MS patients and 26,703 healthy people — and data from two proteome-wide association studies (PWAS).

New research published in the Annals of Clinical and Translational Neurology has identified three genes and their expressed proteins that may be involved in the pathogenesis of multiple sclerosis.

Scientists noted, “Studying the functions of these genes may uncover new information on the mechanisms involved in the development and progression of multiple sclerosis. Our findings shed new light on ...

Abstract Brain proteome-wide association study linking-genes in multiple sclerosis pathogenesis Objectives To identify genes that confer MS risk via the alteration of cis-regulated protein abundance ...

Incidence of multiple sclerosis in China: A nationwide hospital-based study. The Lancet Regional Health. 2020 Aug 6;1:100010. DOI: 10.1016/j.lanwpc.2020.100010 ...

The role for human herpesvirus (HHV)-6A or HHV-6B in multiple sclerosis (MS) pathogenesis has been controversial. Possibly because the damage of the virus infection may occur before onset of clinical ...