Mechanisms of Multiple Sclerosis. The pathogenesis of MS involves the initiation and perpetuation of inflammatory mediators, which leads to apoptosis of oligodendrocytes and damage to the myelin ...

When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered ...

Although the basic pathology of MS was already recognized in the 18th century, its causes and pathogenesis remain elusive. The most widely accepted theory is that MS develops in genetically ...

Epstein-Barr Virus. Epstein-Barr virus (EBV) has long been postulated to play a role in the pathogenesis of MS, but that connection received a solid boost in 2022, when Alberto Ascherio, MD, DrPH ...

Multiple sclerosis (MS) is a common immune-mediated progressive neurodegenerative disease of the CNS that typically manifests with periods of disease activity followed by intervals of remission ...

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease targeting the brain. The pathogenesis of MS remains largely unknown, though brain tissue damage in MS is likely due to immune ...

In fact, a study of 801 MS cases from more than 10 million active-duty military personnel over 20 years found that EBV ...

ST. LOUIS -- African Americans with multiple sclerosis have a more robust immunologic response than whites, which may explain the greater severity of symptoms among blacks, investigators here found.

“Multiple sclerosis (MS) ... “While progress has been made in defining the immune system’s role in MS pathophysiology, the contribution of intrinsic CNS cell dysfunction remains unclear. ...

Following a competitive selection process, Ashlyn Anderson was chosen as the recipient of the inaugural Tanner MS Scholar Award. Ashlyn is a 4 th year PhD student at the University of Alabama at ...