The Israeli military has warned that “all of Israel is under fire” after Iran launched retaliatory strikes on Friday, following Israel’s attacks on Iranian military and nuclear targets.

Iran has fired about 200 ballistic missiles in four barrages and more than 200 drones toward Israeli territory so far in response to multiple waves of Israeli strikes, an Israeli military official said.

Iran launched missiles and drones at Israel in separate barrages overnight Friday in response to airstrikes less than a day earlier that targeted nuclear sites and top commanders in the Islamic nation.

Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

The U.S. military is operating in the air, on land and at sea to shoot down Iranian missiles fired at Israel.

The retaliatory strikes came on Saturday, a day after Israel killed top Iranian military leaders and scientists and destroyed an aboveground nuclear enrichment plant near Natanz.

US intelligence has reported that Iran has 2,000 ballistic missiles, many of which are capable of carrying 900 kg warheads. Iran's goal is for the number of its missiles to exceed the number of Israeli air defense interceptors.

Israel unleashed airstrikes across Iran for a third day and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country