In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

Structural variants in the human genome include cytogenetically detectable and submicroscopic deletions, duplications, large-scale copy-number variants, inversions and translocations. The ability ...

The Noonan lab at Yale University is focused on understanding how HARs contribute to the evolution of uniquely human brain features.

A recent paper provides an updated perspective on the evolutionary history of chelicerates—a diverse and ecologically ...

Based in Reykjavik, Iceland, deCODE genetics is a global leader in analyzing and understanding the human genome. Using its unique expertise and population resources, deCODE has discovered genetic ...

It continues 25 years of research at deCODE genetics into how new diversity is generated in the human genome, and its relationship to health and disease. The new map, appearing today in the online ...

To do this, researchers used prime editing to insert a recognition sequence into the genomes of the human cell lines to target with recombinase—an enzyme that enabled the team to 'shuffle' the genome.

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

In order to exploit its secrets, it is vital that the human genome is fully understood. It enables us to: search for genes linked to different types of disease understand inherited disorders and ...

Solving the evolutionary puzzle of polyploidy: how genome duplication shapes adaptation. ScienceDaily . Retrieved February 16, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250123002057.htm ...

For the new study, the Yale team used advanced techniques to map the genome in three dimensions in order to track how HARs interact with genes in human and chimpanzee neural stem cells. This allowed ...