Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of the CNS. 1 In early disease, active bouts of demyelination are followed by periods of remission, and relapses are ...

Mechanisms of Multiple Sclerosis. The pathogenesis of MS involves the initiation and perpetuation of inflammatory mediators, which leads to apoptosis of oligodendrocytes and damage to the myelin ...

When ocrelizumab became the first FDA-approved treatment for early forms of multiple sclerosis (MS) in 2017, it offered ...

Although the basic pathology of MS was already recognized in the 18th century, its causes and pathogenesis remain elusive. The most widely accepted theory is that MS develops in genetically ...

Epstein-Barr Virus. Epstein-Barr virus (EBV) has long been postulated to play a role in the pathogenesis of MS, but that connection received a solid boost in 2022, when Alberto Ascherio, MD, DrPH ...

Pathogenesis of MS: Molecular mimicry. Experimental virological and immunological studies have disclosed that when a virus attacks the body, ...

Multiple sclerosis (MS) is a common immune-mediated progressive neurodegenerative disease of the CNS that typically manifests with periods of disease activity followed by intervals of remission ...

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease targeting the brain. The pathogenesis of MS remains largely unknown, though brain tissue damage in MS is likely due to immune ...

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease targeting the brain. The pathogenesis of MS remains largely unknown. It is believed that brain tissue damage is due to immune ...

ST. LOUIS -- African Americans with multiple sclerosis have a more robust immunologic response than whites, which may explain the greater severity of symptoms among blacks, investigators here found.

“Multiple sclerosis (MS) ... “While progress has been made in defining the immune system’s role in MS pathophysiology, the contribution of intrinsic CNS cell dysfunction remains unclear. ...