Paramount’s Novocaine made $1.75M in previews — but that’s not just from last night, rather advance screenings from last weekend as well. The R-rated action comedy, which cost a net $18M before P&A, might lead the box office this weekend with anywhere from $8M-$12M,

“Novocaine” only cost $18 million to produce, so (like its main character) it shouldn’t be feeling any pain at the box office. On the flip side, “Mickey 17” cost $118 million to produce and needs around $275 million to $300 million worldwide to make a profit.

The hero at the heart of “Novocaine” can't feel pain. The new film in theaters Friday stars Jack Quaid as Nate, an ordinary guy whose disability becomes his saving grace when attempting to save a hostage from violent criminals.

Actor Jack Quaid stars as a man who can't feel pain in "Novocaine," a new action film that opens in theaters Friday. Quaid, known for his role as Hughie in the hit series "The Boys," plays Nathan Cain,

Jack Quaid discusses the intense preparation for his role in "Novocaine." The action comedy features Quaid as a man who feels no pain.

When the girl of his dreams gets kidnapped, a man turns his inability to feel pain into an unexpected advantage as he fights a bunch of thugs to get her back. That’s the premise of “Novocaine” starring Jack Quaid.