The increasing reliance on hazard ratios for the assessment of clinical trial data prompted this Perspectives article, designed to outline the uses and misuses of this popular statistical value.

When this assumption is plausible, such a ratio estimate may capture the relative difference between two survival curves. However, the clinical meaning of such a ratio estimate is difficult, if not ...

Summary statistics, such as hazard ratios, that are based on models may be difficult to interpret if there are substantial departures from key assumptions, including the assumption of ...

The stratified hazard ratio for death was 0.81 (95% CI, 0.64 to 1.03; P=0.09) . The ... In the updated analysis of PALOMA-3, which was conducted at a data cutoff of October 23, ...

Revascularization of all vessels with stenosis was linked to lower rates of death, another MI, and further revascularization ...

These results include an OS hazard ratio (HR) below 1.00, favoring tivozanib (HR=0.99; 95% CI: 0.76-1.29; p=0.95). An OS hazard ratio assesses the relative risk of death for the entirety of the ...

AVEO Oncology (NASDAQ: AVEO) today announced results from the second prespecified analysis of overall survival (OS) in the TIVO-3 trial. TIVO-3 is the ...