Demyelination affects the brain and spinal cord in MS. Sometimes demyelination causes scarring, often described as plaques. Inflammation, demyelinating changes, scars, and plaques can appear on ...

Multiple sclerosis (MS) causes a specific type of damage, called demyelination, to the central nervous system, including the spinal cord. MS is a neurological disease. It causes the immune system ...

varicella zoster virus among others), and demyelinating disorders (e.g., MS and acute demyelinating encephalomyelitits). More commonly, however, the term optic neuritis is used as a synonym for ...

Because these lesions can be induced experimentally, the model offers a look at the earliest stages of inflammation and immune responses that lead to MS-like demyelination. One key player identified ...

In MS, slowly expanding lesions were linked to more myelin loss in brain regions of damage and in normal-appearing brain ...

Myelin, the protective sheath around nerve fibers, plays a crucial role in brain communication. It ensures fast and efficient ...

Myrobalan's experimental therapy MRO-002 is a GPR17 antagonist that's made to promote myelin repair in people with MS and ...

As shown in preclinical models of MS, it can directly stabilize the myelin sheath surrounding nerve fibers and thus provide protection from demyelination. MS is a disease characterized by ...

Demyelinating optic neuritis (DON) is a hallmark feature of multiple sclerosis (MS) and often occurrs as the heralding event of the disease. Optical coherence tomography has revolutionized the ...